Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
XRCC3 | O43542 | X-ray repair cross complementing 3 | 1.9E-10 | 0.505 | 0.769 | |
XRCC2 | O43543 | X-ray repair cross complementing 2 | 4.0E-07 | 0.512 | 0.731 | |
XRCC1 | P18887 | X-ray repair cross complementing 1 | 6.3E-09 | 0.421 | 0.923 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TGFBR1 | P36897 | transforming growth factor beta receptor 1 | Kinase | 0.85 | 0.451 | 0.885 |
TEK | Q02763 | TEK receptor tyrosine kinase | Kinase | 1.00 | 0.462 | 0.692 |
TCF7L2 | Q9NQB0 | transcription factor 7 like 2 | 1.00 | 0.485 | 0.846 | |
STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 |
SOAT1 | P35610 | sterol O-acyltransferase 1 | Enzyme | 7.4E-10 | 0.424 | 0.846 |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
RASSF1 | Q9NS23 | Ras association domain family member 1 | Enzyme modulator | 4.9E-06 | 0.420 | 0.808 |
POLH | Q9Y253 | DNA polymerase eta | 3.5E-09 | 0.663 | 0.462 | |
PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
NLRP2 | Q9NX02 | NLR family pyrin domain containing 2 | 1.4E-38 | 0.515 | 0.731 | |
NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
MSH3 | P20585 | mutS homolog 3 | Nucleic acid binding | 7.4E-31 | 0.474 | 0.769 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MIR21 | microRNA 21 | 0.363 | 0.846 | |||
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |